Pt(II) and Pt(IV)-tagged nanoparticles have been synthesized according to the template method for the identification of pesticides. Their morphologies have been investigated using scanning electron microscopy and characterized by means of spectral measurements. Then, acetylcholinesterase (AChE) was immobilized onto the nanoparticles. The AChE immobilized Pt(II) and Pt(IV)-tagged nanomaterials show high reusability and storage capacity. The catalytic activity of AChE followed Michaelis–Menten kinetics. Assays for enzyme activity measurements demonstrate that the nanospheres tagged with Pt(II) have a much better performance than those with Pt(IV). Furthermore, whether or not there was any interaction between the immobilized enzyme and 1-naphthyl-N-methylcarbamate, which is a carbamate insecticide, was examined.

A series of new compounds containing formyl and imine group were synthesized. New formyl-substituted compounds were prepared by the reaction of 1,2-bis(bromomethyl)benzene with benzaldehyde derivatives in the presence of NaOH. New bis-crown ether imine compounds were prepared by the condensation of corresponding aldehydes with 4′-aminobenzo-15-crown-5. Sodium complexes of the bis-crown ethers form crystalline 2:1 (Na+:ligand) stoichiometries were also been synthesized. The prepared compounds were structurally confirmed by analytical and spectral data and evaluated for their antibacterial and antifungal activities. The results show that the antibacterial activity of compounds including o-methoxy group was significantly higher against S. epidermis compared to the other studied antimicrobial group.

New nanosphere supports were prepared and characterized for the immobilization of glucose oxidase from Aspergillus niger. Nanoparticles ((APS-tio), (APS-tioCH3), and (APS-tioCl)) modified (aminomethyl)polystyrene (APS) with some tyophenealdehyde derivatives were synthesized by means of condensation and we investigated the enzymatic properties of glucose oxidase enzyme (GOx) immobilized on them. Modified polystyrene was characterized by IR spectra, gel permeation chromatography and scanning electron microscopy. Immobilized GOx on (APS-tioCH3) showed a optimum pH, whereas immobilized GOx on (APS-tio) and (APS-tioCl) performed the optimum condition at two pHs.

The aim of this work was to investigate the antibacterial and antifungal activities of novel d-amino acid-Schiff bases including fluorine atom and their Cr(III) and Ni(II) complexes. All these substances have been examined for antibacterial activity against pathogenic strains Listeria monocytogenes 4b ATCC19115, Staphylococcus aureus ATCC25923, Escherichia coli ATCC1280, Salmonella typhi H NCTC 901.8394, Brucella abortus (A.99, UK-1995) RSKK03026, Staphylococcus epidermis sp., Micrococus luteus ATCC9341, and Shigella dysenteriatyp 10 NCTC 9351, and antifungal activity against Candida albicans Y-1200-NIH, Tokyo. The antimicrobial test results of these amino acid-Schiff base complexes exhibited better activity than some known antibiotics. In particular, diamagnetic Ni(II) complexes were more potent bactericides than all of the substances synthesized.

A new amine containing selenium and their five imine, (SeSchX)(X: -H, F, Cl, Br, CH3), and Ni (II) complexes, [Ni(SeSchX)(H2O)2]Cl/[Ni(SeSchCl)(H2O)Cl], were synthesized. The compounds were characterized by means of elemental analyses, 13C and 1H NMR (for imine), FT-IR, UV–Visible spectroscopy, TGA/DTA and elemental analyses. [Ni(SeSchCl)(H2O)Cl] complex from Ni(II) complexes changes color from yellow to orange in the range pH 5–7. [Ni(SeSchCl)(H2O)Cl] complex has ligand-to-metal charge-transfer (LMCT) transitions in the basic medium. Excitation characteristics and energetic of [Ni(SeSchCl)(H2O)Cl] complex, examined via TD-DFT calculations, reveals transitions of LMCT and π → π* character that matches the experimental values. [Ni(SeSchCl)(H2O)Cl] complex showed the highest antibacterial activity when compared to other complexes reported in this work.Graphical abstractFive new Schiff bases involving Selenium [(SeSchX)(X: -H, F, Cl, Br, CH3)] and Ni(II) complexes ([Ni(SeSchX)(H2O)2]Cl/[Ni(SeSchCl)(H2O)Cl]) are synthesized and characterized. [Ni(SeSchCl)(H2O)Cl] complex exhibits metal-centered color-changing in between pH 5–7 and is a more potent bactericide than other complexes.Highlights► Novel Ni(II)-tetrahedral complex with selenium ligand has been synthesized by means of template method and characterized. ► [Ni(SeSchCl)(H2O)Cl] complex shows different properties of synthesized Ni(II) complexes. ► This complex changes color from yellow to orange in the range pH 5–7. ► [Ni(SeSchCl)(H2O)Cl] complex is more potent bactericides than all of the substances synthesized.

A series of some novel Ethyl 2-((1-hydroxynaphthalen-2-yl)methyleneamino)-5,6-dihydro-4H-cyclopenta[b]thiopehene-3-carboxylate, Ethyl 2-((1-hydroxynaphthalen-2-yl)methyleneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate, Ethyl 2-((1-hydroxynaphtalen-2-yl)methyleneamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate and their Cr(III) and Zn(II) complexes have been synthesized. All of these substances have been examined for antibacterial activity against pathogenic strains Listeria monocytogenes 4b (ATCC-19115), Staphylococcus aureus (ATCC25923), Proteus OX2 Wrah (ETS.40-A-4), Escherichia coli (ATCC-1280), Salmonella typhi H (NCTC-901.8394), Pseudomonas putida sp., Brucella abortus (A.99, UK-1995) RSKK-03026. Sh. boydii type 11 (Pasteur51.6), Sh. boydii type 16 (cHe 67.11), Sh. boydii type 6 (RSKK-96043), and antifungal activity against Candida albicans (Y-1200-NIH, Tokyo). Some of the compounds exhibited activity comparable to ampicillin ofloxacin, nystatin, kanamycin, sulphamethoxazol, amoxycillin, and chloroamphenicol. Most of the studied compounds were found effective against bacteria studied and yeast.

Pt(II) and Pt(IV)-tagged nanoparticles have been synthesized according to the template method for the identification of pesticides. Their morphologies have been investigated using scanning electron microscopy and characterized by means of spectral measurements. Then, acetylcholinesterase (AChE) was immobilized onto the nanoparticles. The AChE immobilized Pt(II) and Pt(IV)-tagged nanomaterials show high reusability and storage capacity. The catalytic activity of AChE followed Michaelis–Menten kinetics. Assays for enzyme activity measurements demonstrate that the nanospheres tagged with Pt(II) have a much better performance than those with Pt(IV). Furthermore, whether or not there was any interaction between the immobilized enzyme and 1-naphthyl-N-methylcarbamate, which is a carbamate insecticide, was examined.