855-31-2|1H-Pyrrole, 1-(4-methoxyphenyl)-2,5-diphenyl-

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CAS: 855-31-2

MF: C23H19NO

MW: 325.40306

Synonyms: 1H-Pyrrole, 1-(4-methoxyphenyl)-2,5-diphenyl-

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Ruimao Hua

Tsinghua University

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CuCl-catalyzed cycloaddition of 1,3-butadiynes with primary amines: an atom-economic process for synthesis of 1,2,5-trisubsituted pyrroles

Co-reporter: Qingwei Zheng, Ruimao Hua

pp: 4512-4514

Publication Date(Web):25 August 2010

DOI: 10.1016/j.tetlet.2010.06.092

1,3-Butadiynes underwent inter- and intramolecular double hydroamination with primary amines in the presence of CuCl at 100 °C to afford 1,2,5-trisubsituted pyrroles in good to high yields. Image for unlabelled figure

Bernard T. Golding

Newcastle University

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Ian R. Hardcastle

Newcastle University

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